I am going to try to answer this question by comparing it to a couple other areas of our lives where we might consider a family member to help.
How about buying or selling a home? Maybe if they are licensed and have experience. You would want someone that knows the market and is able to find you the best possible deal.
How about tutoring or teaching your kids? Yes, if they have spent the time educating other children and know how to engage and motivate your child.
The same holds true for a wedding officiant. You want to have someone who possesses the ability to speak in front of a large audience. You want someone that knows how to keep the ceremony on track in case the unexpected (i.e. the best man forgets the rings) happens. You want to have someone that has worked with the various vendors and venues before.
So should you have a family member officiate your ceremony? Maybe. It all depends if they are experienced and have the right skills for the job.